Meet the Mark I

The fastest, most accessible full body scanner ever.

Mark I will be able to autonomously scan your whole body for existential risks in 10 minutes, generating extensive quantitative anatomical data with no radiation, breath holds, or claustrophobia. The Mark I will deliver the speed, reproducibility, safety and comfort needed for whole body MRI to power Digital Twins and Large Biological Models at population scale.

Problems with MRI today.

Imprecise & not reproducible

Large variances between equivalent scans over time are caused by patient movement, scanner configuration changes, and differences between scanners, operators and interpreting radiologists.

Not patient friendly

According to our research study, 40% of people we paid to participate were unable to complete a whole body MRI due to claustrophobia or the breath hold requirements.

Expensive & slow

Requires significant infrastructure to set up and operate including a shielded room, quench vents and liquid helium, as well as a highly skilled human operator. Comprehensive whole body scans take at least 60 minutes.

Introducing Mark I

Scanners today are slow, expensive, uncomfortable and generate qualitative outputs that are not reproducible. This makes them ill equipped to enable the recurring whole body scans at population scale we need to unlock a truly preventive healthcare system.

The Mark I — the first whole body MRI in an upright geometry with the largest field of view ever in an open magnet — will solve these problems.

Unrivaled Speed

Collects 100x more data per minute — generate any contrast from one 10 minute quantitative scan with even faster successive scans.

>75% cheaper

To deploy, operate and maintain with minimal special infrastructure, no liquid helium and no shielded room required

Quantitative

Generates multi-parametric quantitative data that is reproducible across scanners — optimal for AI interpretation

AI radiology tools

Our Anatomical Foundation Model and other AI tools, built in

Autonomous

No highly skilled labor required to run any scan

Comfortable

Patients can sit, stand or lie down, with no breath holds required

Note: The Mark I has not yet been approved by the FDA.

The technologies behind the Mark I

The Mark I’s speed, reproducibility, low cost, safety and comfort will be enabled by these breakthrough technologies — each of which have been validated on both third-party and our own hardware.

TENSOR FIELD MAPPING (TFM)

Revolutionizing quantitative MRI

Generate any MRI contrast from a single fast, free breathing acquisition

Precise, reproducible outputs across variable scan conditions

Unrivaled tissue property quantification

Quantitative maps measuring physical tissue properties at each spatial location are retrieved from a single scan

Any conventional MRI contrast can be generated from those quantitative maps, without additional scan time

Tensor Field Mapping (TFM) ushers in a new era of imaging technology. Our revolutionary numerical framework enables quantitative MRI in the time domain, paving the way for fast, accurate, and cheap multi-parameter tissue property quantification.

TFM is a groundbreaking solution, meticulously designed to tackle the challenges posed by the non-ideal conditions of MRI acquisitions. Through rigorous modeling of multi-physics phenomena, TFM represents a paradigm shift, enabling the generation of any MRI contrast from a single fast, free breathing acquisition. Leveraging our proprietary GPU-based framework, TFM makes real-time 3D quantitative MRI possible directly on the Mark I.

Quantitative maps measuring physical tissue properties at each spatial location are retrieved from a single scan

Any conventional MRI contrast can be generated from those quantitative maps, without additional scan time

Unrivaled scan time

The Mark I’s unrivaled whole body scan time is supported by two key acquisition acceleration technologies, Inspire and Delta.

INSPIRE

>8x acceleration enabled by best-in-class, physics model based image reconstruction

Best in class undersampling reconstruction without image priors

Fully deterministic, meaning no training data required and no risk of hallucinations

8x acceleration on a 12 channel coil and even higher accelerations with more coils

0min
10min

INSPIRE is a framework for accelerated parallel imaging that achieves best in class image reconstruction from under-sampled data without the use of any image priors. It achieves this level of performance by incorporating a physics-based model into the estimation of coil sensitivities. The final image reconstruction does not involve any AI inference, avoiding the risk of hallucinations completely. The framework is generalized over any B0 and B1 field, and can be used in combination with our other techniques in extremely inhomogeneous fields.

DELTA

Your next whole body scan, at least 10 times faster than the last one

10-20x acceleration for repeat scans, making it optimized for recurring preventive screens and longitudinal tracking

Automatically gathers more information in areas with the greatest changes

0min
10min

Delta is an advanced acquisition acceleration technique that achieves very high acceleration rates by using each individuals prior scan as a baseline — like MPEG for the body. Unlike other acceleration techniques which make assumptions that lead to image quality degradations at very high acceleration factors, Delta maintains quality and small details even at very high acceleration. Delta leverages the historical Gemini Digital Twin profile and scans to optimize scan time and automatically gather more information in areas with the greatest changes where there may be more risk.

OTTO

Autonomous scans — just press one button to scan

Reduce errors, rescans & table time

Improved consistency & reproducibility

No highly skilled labor required

  • Liver

  • Spleen

  • Right Kidney

  • Left Kidney

One of the biggest sources in variability between scans is the operator. Otto is a AI framework controlling patient table position and slice prescriptions in a fully automated manner, ensuring reproducible and accurate acquisitions every single visit. Otto performs this task much faster and more consistently than a human operator would, substantially reducing the table time for the patient and removing the need for highly skilled labor.

  • Liver

  • Spleen

  • Right Kidney

  • Left Kidney

State of the art design tools

To enable the creation of a revolutionary new scanner, we had to reinvent the design tools.

MAGNETO

Integrated suite of analytical and FEA tools for rapid MR device component design

Rapidly generate candidate designs from a set of constraints

Frictionless interactions with commercial simulation products

Magneto is a suite of tools developed specifically for the design of magnetic resonance devices. Featuring a suite of optimization tools and analytical EM solvers for coils of a variety of geometries it can rapidly generate candidate designs from a set of constraints. The tools interact with commercial simulation products as well, greatly speeding up, by automation, the iterative design process involving commercial solvers.

PULSAR

Highly efficient pulse sequence programming and simulation environment

Compact, easy to use Python-based sequence programming environment

Built in simulation environment; integrated with Magneto and other Q Bio tools

Pulsar is a next generation platform for pulse sequence design. It includes a compact and easy to use Python-based library of modular objects that simplify the development of complex pulse sequences, allowing the scientist to focus on the physics rather than specifics of the machine. Pulsar also comes with a simulation environment that provides full simulation of the sequence on digital phantoms and arbitrary field configurations that can be imported from Magneto. This allows the scientist to assess sequence performance on a wide range of real and virtual configurations while exploring the limits of new hardware designs.

Partner with Q Bio

Partner with us to test Q Bio’s revolutionary Digital Twin and quantitative MRI technologies in your health system.

Gemini Platform partnership

A Gemini Platform partnership will empower you to offer your patients the most comprehensive view of their health and risks available today.

Partner with us
What you'll need:

Your own MRI hardware

Capacity to do the lab tests and gather vitals

Perform exam and review results with your patients

We will partner with you to seamlessly integrate data from the exam you perform and run our Anatomical Foundation Model, if you choose to partner with us to test it under a research protocol, to derive unparalleled quantitative data and insights from the MRI scans. This will be combined with your patient’s EHR, lifestyle and other data to create their Gemini Digital Twin Dashboard — the most comprehensive view of their health and risks available today.

Mark I partnership

The Mark I will be the fastest, most accessible full body scanner ever. Partner with us to test it in your health system under a research protocol upon its release.

Partner with us
Major benefits:

Unrivaled speed, collects 100x more data per minute — generate any contrast from one 10 minute scan

Integrated AI radiology tools, including our Anatomical Foundation Model

Autonomous, no highly skilled labor required to run any scan

75% cheaper, minimal special infrastructure and no shielded room required

Comfortable, you can sit, stand or lie down with no breath holds required

Quantitative, generates reproducible data optimized for machine interpretation

Our Technologies

Q Bio is developing three technology pillars that will ultimately be vertically integrated and combined with commodity vitals & biochemistry collection to enable Digital Twins and Large Biological Model-powered personalized health forecasts at population scale.